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OJBTM
Online Journal of Bioinformatics ©
Volume 16 (1): 1-7, 2015.
Systems biology
prediction for evolutionary process of coloured vision in mammals.
1Shivani Sharma, 2Prashant Saxena*
1Department of Life science, Institute of
applied medicine and research, Duhai, Ghaziabad,
Uttar Pradesh. 2Department of Bioinformatics, Sathyabama
University, Chennai, Tamilnadu, India.
ABSTRACT
Sharma S, Saxena P., Systems
biology prediction of evolutionary process for coloured vision in mammals, Onl J Bioinform, 16 (1): 1-7, 2015. Since Darwin, genetic change has been
considered to be a direct indicator of variation in phenotype. Recently it has
been proposed that epigenetic developmental processes affect phenotype shifting
focus from a linear genotype-phenotype map to a non-linear G-P one. LWS opsin
gene has a role in trichromatic vision in human beings and other mammals. LWS
opsin gene is particularly sensitive to the green-yellow color
range differentiating between vivid colors more
clearly. We describe evolution of colour vision in mammals through the LWS
long-wave sensitive gene mutations which lead to the different phenotypes. The
opsin genes LWS, MWS and SWS
contribute to a variable colour vision spectrum and we show that
genotypic variation alone is not responsible for resulting genotypes in vision.
KEYWORDS: Evolution, Opsin gene,
genotype, phenotype, color vision.
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