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OJBTM
Online Journal of Bioinformatics©
Volume 8 (1): 41-44, 2007.
Database and interactome
map of genes involved in oral cancer
1Bioinformatics centre (BTIS Sub-DIC),
Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial
Centre, Kharghar, Navi
Mumbai, India
ABSTRACT
Gadewal NS, Zingde SM.,
Database and interactome
map of genes involved in oral cancer, Onl J Bioinform, 8 (1) 41-44, 2007. In the post
genomic era, efforts to understand oral cancer are aimed at obtaining genomic
and proteomic profiles for cancer management. The database in this report information and external links for 242 genes
involved in oral cancer, interactions between them, their role in the biology
of oral cancer, along with clinical relevance. Each gene gives detailed
information on aliases, function, chromosomal location, mutations and
SNPs, mRNA expression, protein information, pathways involved and interacting
proteins, expression of genes in different tissues, and clinical correlates.
For querying the database a search engine retrieves the genes by symbol, name,
chromosomal location, gains and losses of chromosomal regions and molecular
weight. Interactome maps have been generated for the
genes that are categorized into important biological processes and molecular
functions based on Gene-Ontology.
KEYWORDS: Oral cancer, Database, Interactome map
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