MAIN

 


©1996-2019. All Rights Reserved. Online Journal of Bioinformatics . You may not store these pages in any form except for your own personal use. All other usage or distribute on is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJB publications. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the editors. This journal satisfies the refereeing requirements (DEST) for the Higher Education Research Data Collection (Australia). Linking:To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page.


 

OJBTM
Online Journal of Bioinformatics©
Volume 13(1):33-40, 2012


Model and molecular docking substrate stabilization of Microsporum canis keratinase

 

MVK Karthik, Hanan Syed, Tridisha Goswami, Pratyoosh Shukla

 

Birla Institute of Technology (Deemed University), Mesra, Ranchi-835215, Jharkhand, India.

 

ABSTRACT

 

Karthik MVK, Syed H, Goswami T, Shukla P., Model and molecular docking substrate stabilization of Microsporum canis keratinase, Online J Bioinform, 13(1):33-40, 2012. Keratinophilic fungi vigorously degrade keratin. Keratinase of Microsporum canis was modeled with an accuracy RMS Z score of 1.432 using PROVE software. Molecular docking between modeled keratinases from species of keratinophilic fungi viz. Microsporum canis with different types of keratins as substrates was performed with scores of -451.89 kj/mol and -262.37 kj/mol, respectively. Arg1031 is conserved in keratinase while interacting with both keratins

 

Key words: Keratinophilic fungi, keratin, keratinase, Microsporum canis, molecular docking.


MAIN

 

FULL-TEXT(SUBSCRIPTION OR PURCHASE TITLE $25USD)