MAIN


©1996-2019.  All Rights Reserved. Online Journal of Bioinformatics . You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the  before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJB publications. This article may be copied once but may not be, reproduced or  re-transmitted without the express permission of the editors. This journal satisfies the refereeing requirements (DEST) for the Higher Education Research Data Collection (Australia). Linking: To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page.


OJBTM

Online Journal of Bioinformatics ©

Volume 18(1):39-46, 2017.


 Model docking of human 2,3 dioxygenase to Adhatoda vasica, Biophytum sensitivum

and Caesalpinia bonduc extracts for prevention of cataract.

 

Vrukonda Nagalaxmi, Turlapati NagaRaju.

 

Department of Zoology, Physiology Division and University College of Science, Osmania University, Hyderabad-07, India.

 

ABSTRACT

 

Nagalaxmi V, NagaRaju T., Model docking of human indoleamine 2,3 dioxygenase to Adhatoda vasica, Biophytum sensitivum and Caesalpinia bonduc for prevention of cataract. Onl J Bioinform., 18(1):39-46, 2017. Gas chromatography and mass spectrometry was used to identify compounds present in ethanolic extracts of Adhatoda vasica, Biophytum sensitivum and Caesalpinia bonduc, docked In silico to indoleamine 2,3 dioxygenase which has a role in causing cataract. Results suggested that of 15 compounds tested, Androstane 3,17-dione had greatest binding affinity with Indoleamine 2, 3 dioxygenase.

 

Key words: Cataracts, Model, Docking, Indoleamine 2, 3 dioxygenase.


MAIN

 

FULL-TEXT (SUBSCRIPTION OR PURCHASE TITLE $25USD)